Tripsin

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Tripsin
1UTN.png
Identifikatori
EC broj 3.4.21.4
CAS broj 2594141
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Tripsin (EC 3.4.21.4, alfa-tripsin, beta-tripsin, kokunaza, parenzim, parenzimol, triptar, tripur, pseudotripsin, tripcelim, sperm receptorska hidrolaza) je enzim.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju

Preferentno odvajanje: Arg-, Lys-

Jednolančani polipeptid goveđeg beta-tripsina se formira iz tripsinogena razlaganjem jedne peptidne veze.

Reference[uredi - уреди | uredi izvor]

  1. Huber, R. and Bode, W. (1978). "Structural basis of the activation and action of trypsin". Acc. Chem. Res. 11: 114–122. 
  2. Walsh, K.A. (1970). "Trypsinogens and trypsins of various species". Methods Enzymol. 19: 41–63. 
  3. Read, R.J., Brayer, G.D., Jurásek, L. and James, M.N.G. (1984). "Critical evaluation of comparative model building of Streptomyces griseus trypsin". Biochemistry 23: 6570–6575. PMID 6442164. 
  4. Fiedler, F. (1987). "Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin". Eur. J. Biochem. 163: 303–312. PMID 3643848. 
  5. Fletcher, T.S., Alhadeff, M., Craik, C.S. and Largman, C. (1987). "Isolation and characterization of a cDNA encoding rat cationic trypsinogen". Biochemistry 26: 3081–3086. PMID 3112218. 
  6. Polgár, L. (1987). "Structure and function of serine proteases". u: Neuberger, A. and Brocklehurst, K.. New Comprehensive Biochemistry: Hydrolytic Enzymes. 16. Amsterdam: Elsevier. str. 159-200. 
  7. Tani, T., Kawashima, I., Mita, K. and Takiguchi, Y. (1990). "Nucleotide sequence of the human pancreatic trypsinogen III cDNA". Nucleic Acids Res. 18: 1631–1631. PMID 2326201. 

Literatura[uredi - уреди | uredi izvor]

  • Polgár, L. (1987). "Structure and function of serine proteases". u: Neuberger, A. and Brocklehurst, K.. New Comprehensive Biochemistry: Hydrolytic Enzymes. 16. Amsterdam: Elsevier. str. 159-200. 

Spoljašnje veze[uredi - уреди | uredi izvor]