Tironamin

Tironamin
	4-[4-(2-Aminoetil)fenoksi]fenol
Identifikacija
CAS registarski broj	500-78-7
PubChem	3083601
ChemSpider	2340781
MeSH	thyronamine
ChEMBL	CHEMBL201896
Jmol-3D slike	Slika 1
SMILES
	O(c1ccc(cc1)CCN)c2ccc(O)cc2
InChI
	InChI=1S/C14H15NO2/c15-10-9-11-1-5-13(6-2-11)17-14-7-3-12(16)4-8-14/h1-8,16H,9-10,15H2 ; Kod: OVUVNKDANCKDCK-UHFFFAOYSA-N InChI=1/C14H15NO2/c15-10-9-11-1-5-13(6-2-11)17-14-7-3-12(16)4-8-14/h1-8,16H,9-10,15H2; Kod: OVUVNKDANCKDCK-UHFFFAOYAP
Svojstva
Molekulska formula	C14H15NO2
Molarna masa	229.27 g mol−1
	(šta je ovo?) (verifikuj) ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

Tironamin se odnosi na molekul, i njegove derivate: familiju dekarboksilisanih i dejodiranih metabolita tiroidnih hormona tiroksina (T4) i 3,5,3'-trijodotironina (T3).

Tipovi[uredi - уреди | uredi izvor]

Ova grupa obuhvata:

Tironamin (T0AM)
3-Jodotironamin (T1AM), trag amin prisutan u nervnom sistemu. On je potencijalni prirodni ligand za trag amin-asocirani receptor TAAR1 (TAR1), G protein spregnuti receptor lociran u ćelijskoj membrani^[5]
3,5-Dijodotironamin (T2AM)
3,5,3'-Trijodotironamin (T3AM)

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. PMID 20331846. doi:10.1186/1758-2946-2-3. edit
↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. PMID 21948594. doi:10.1093/nar/gkr777. edit
↑ Piehl S, Hoefig CS, Scanlan TS, Köhrle J (2011). "Thyronamines - Past, Present, and Future". Endocrine Reviews 32 (1): 64–80. PMID 20880963. doi:10.1210/er.2009-0040.

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