Tiol sulfotransferaza
Prijeđi na navigaciju
Prijeđi na pretragu
| Tiol sulfotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.8.2.16 | ||||||||
| CAS broj | 70356-45-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Tiol sulfotransferaza (EC 2.8.2.16, fosfoadenililsulfat-tiolna sulfotransferaza, PAPS sulfotransferaza, adenozin 3'-fosfat 5'-sulfatofosfatna sulfotransferaza) je enzim sa sistematskim imenom 3'-fosfoadenilil-sulfat:tiol S-sulfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3'-fosfoadenilil sulfat + tiol adenozin 3',5'-bisfosfat + S-alkil tiosulfat
Ovaj enzuim takođe deluje na ditiole.
Reference[uredi | uredi kod]
- ↑ Schmidt, A. (1976). „The adenosine-5′-phosphosulfate sulfotransferase from spinach (Spinacea oleracea L.). Stabilization, partial purification, and properties”. Planta 130: 257-263.
- ↑ Schmidt, A. and Christen, U. (1979). „A PAPS-dependent sulfotransferase in Cyanophora paradoxa inhibited by 5′-AMP, 5′-ADP and APS”. Z. Naturforsch. C: Biosci. 34: 222-228.
- ↑ Tsang, M. (1976). „L.-S. and Schiff, J.A. Studies of sulfate utilization by algae. 17. Reactions of the adenosine 5′-phosphosulfate (APS) sulfotransferase from Chlorella and studies of model reactions which explain the diversity of side products with thiols”. Plant Cell Physiol. 17: 1209-1220.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.