Tabersonin 16-O-metiltransferaza
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| Tabersonin 16-O-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.94 | ||||||||
| CAS broj | 100984-95-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Tabersonin 16-O-metiltransferaza (EC 2.1.1.94, 11-demetil-17-deacetilvindolinska 11-metiltransferaza, 11-O-demetil-17-O-deacetilvindolinska O-metiltransferaza, S-adenozil-L-metionin:11-O-demetil-17-O-deacetilvindolinska 11-O-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:16-hidroksitabersonin 16-O-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + 16-hidroksitabersonin S-adenozil-L-homocistein + 16-metoksitabersonin
Ovaj enzim učestvuje u biosintezi vindolina iz tabersonina kod Madagascar periwinkle.
Reference[uredi | uredi kod]
- ↑ De Luca, V., Balsevich, J., Tyler, R.T., Eilert, U., Panchuk, B.D. and Kurz, W.G.W. (1986). „Biosynthesis of indole alkaloids - developmental regulation of the biosynthetic-pathway from tabersonine to vindoline in Catharanthus roseus”. J. Plant Physiol. 125: 147-156.
- ↑ Fahn, W., Laussermair, E., Deus-Neumann, B. and Stöckigt, J. (1985). „Late enzymes of vindoline biosynthesis. S-Adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methylase and unspecific acetylesterase”. Plant Cell Rep. 4: 337-340.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.