Tiamin difosfokinaza
(Preusmjereno sa stranice TPTase)
| Tiamin difosfokinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.6.2 | ||||||||
| CAS broj | 9026-24-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Tiamin difosfokinaza (EC 2.7.6.2, tiaminska kinaza, tiaminska pirofosfokinaza, ATP:tiamin pirofosfotransferaza, tiaminska pirofosfokinaza, tiaminska pirofosfotransferaza, tiaminokinaza, tiamin:ATP pirofosfotransferaza, TPTaze) je enzim sa sistematskim imenom ATP:tiamin difosfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + tiamin AMP + tiamin difosfat
- ↑ Leuthardt, F. and Nielsen, H. (1952). „Phosphorylation biologique de la thiamine”. Helv. Chim. Acta 35: 1196-1209.
- ↑ Shimazono, N., Mano, Y., Tanaka, R. and Kajiro, Y. (1959). „Mechanism of transpyrophosphorylation with thiamine pyrophosphokinase”. J. Biochem. (Tokyo) 46: 959-961.
- ↑ Steyn-Parvé, E.P. (1952). „Partial purification and properties of thiaminokinase from yeast”. Biochim. Biophys. Acta 8: 310-324. PMID 14934742.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.