Superoksid reduktaza
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Superoksid reduktaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.15.1.2 | ||||||||
CAS broj | 250679-67-5 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Superoksid reduktaza (EC 1.15.1.2, neelaredoksin, desulfoferodoksin) je enzim sa sistematskim imenom rubredoksin:superoksid oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- redukovani rubredoksin + superoksid + 2 H+ rubredoksin +H2O2
Ovaj enzim sadrži gvožđe nevezano za hem.
Reference[uredi | uredi kod]
- ↑ Jenney, F.E., Jr., Verhagen, M.F.J.M., Cui, X. and Adams, M.W.W. (1999). „Anaerobic microbes: Oxygen detoxification without superoxide dismutase”. Science 286: 306-309. PMID 10514376.
- ↑ Yeh, A.P., Hu, Y., Jenney, F.E., Jr., Adams, M.W.W. and Rees, D.C. (2000). „Structures of the superoxide reductase from Pyrococcus furiosus in the oxidized and reduced states”. Biochemistry 39: 2499-2508. PMID 10704199.
- ↑ Lombard, M., Fontecave, M., Touati, D. and Niviere, V. (2000). „Reaction of the desulfoferrodoxin from Desulfoarculus baarsii with superoxide anion. Evidence for a superoxide reductase activity”. J. Biol. Chem. 275: 115-121. PMID 10617593.
- ↑ Abreu, I.A., Saraiva, L.M., Carita, J., Huber, H., Stetter, K.O., Cabelli, D. and Teixeira, M. (2000). „Oxygen detoxification in the strict anaerobic archaeon Archaeoglobus fulgidus: superoxide scavenging by neelaredoxin”. Mol. Microbiol. 38: 322-334. PMID 11069658.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.