Scitalonska dehidrataza
Izgled
Scitalonska dehidrataza | |||||||||
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Identifikatori | |||||||||
EC broj | 4.2.1.94 | ||||||||
CAS broj | 118901-79-4 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Scitalonska dehidrataza (EC 4.2.1.94, scitalonska 7,8-hidrolijaza) je enzim sa sistematskim imenom scitalon 7,8-hidrolijaza (formira 1,3,8-trihidroksinaftalen).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- scitalon 1,3,8-trihidroksinaftalen + H2O
Ovaj enzim zajedno sa enzimom EC 1.1.1.252, tetrahidroksinaftalenskom reduktazom, učestvuje u biosintezi melanina u patogenim gljivama.
- ↑ Butler, M.J., Lazarovits, G., Higgins, V.J. and Lachance, M.-A. (1988). „Partial-purification and characterization of a dehydratase associated with the pentaketide melanogenesis pathway of Phaeococcomyces sp and other fungi”. Exp. Mycol. 12: 367-376.
- ↑ Tajima, S., Kubo, Y., Furusawa, I. and Shishiyama, J. (1989). „Purification of a melanin biosynthetic enzyme converting scytalone to 1,3,8-trihydroxynaphthalene from Cochliobolus miyabeanus”. Exp. Mycol. 13: 69-69.
- ↑ Wheeler, M.H. and Greenblatt, G.A. (1988). „The inhibition of melanin biosynthetic reactions in Pyricularia oryzae' by compounds that prevent rice blast disease”. Exp. Mycol. 12: 151-160.
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- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
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