Polinukleotid adenililtransferaza

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Polinukleotid adenililtransferaza
Identifikatori
EC broj 2.7.7.19
CAS broj 9026-30-6
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Polinukleotid adenililtransferaza (EC 2.7.7.19, NTP polimeraza, RNK adenilatirajući enzim, AMP polinukleotidileksotransferaza, ATP-polinukleotid adenililtransferaza, ATP:polinukleotidileksotransferaza, poli(A) polimeraza, poli(A) sintetaza, poliadenilatna nukleotidiltransferaza, poliadenilatna polimeraza, poliadenilatna sintetaza, poliadenilno kiselinska polimeraza, poliadenilna polimeraza, terminalna riboadenilatna transferaza, poli(A) hidrolaza, RNK formirajući faktori, PF1, adenozin trifosfat:ribonukleinska kiselina adenililtransferaza) je enzim sa sistematskim imenom ATP:polinukleotid adenililtransferaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + RNKn \rightleftharpoons difosfat + RNKn+1

Ovaj enzim takođe u izvesnoj meri deluje sa CTP.

Reference[uredi - уреди]

  1. August, J.T., Ortiz, P.J. and Hurwitz, J. (1962). "Ribonucleic acid-dependent ribonucleotide incorporation. I. Purification and properties of the enzyme". J. Biol. Chem. 237: 3786-3793. PMID 13965521. 
  2. Edmonds, M. and Abrams, R. (1960). "Polynucleotide biosynthesis: formation of a sequence of adenylate units from adenosine triphosphate by an enzyme from thymus nuclei". J. Biol. Chem. 235: 1142-1149. PMID 13819354. 
  3. Gottesman, M.E. and Canellakis, E.S. (1966). "The terminal nucleotidyltransferases of calf thymus nuclei". J. Biol. Chem. 241: 4339-4352. PMID 4288534. 
  4. Krakow, J.S., Coutsogeorgopoulos, C. and Canellakis, E.S. (1962). "Studies on the incorporation of deoxyribonucleic acid". Biochim. Biophys. Acta 55: 639-650. PMID 14459258. 
  5. Mans, R.J. and Walter, T.J. (1971). "Transfer RNA-primed oligoadenylate synthesis in maize seedlings. II. Primer, substrate and metal specificities and size of product". Biochim. Biophys. Acta 247: 113-121. PMID 4946277. 
  6. Sheldon, R., Jurale, C. and Kates, J. (1972). "Detection of polyadenylic acid sequences in viral and eukaryotic RNA(poly(U)-cellulose columns-poly(U) filters-fiberglass-HeLa cells-bacteriophage T4)". Proc. Natl. Acad. Sci. USA 69: 417-421. PMID 4501121. 

Literatura[uredi - уреди]

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