Polinukleotid 5'-hidroksil-kinaza
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| Polinukleotid 5'-hidroksil-kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.1.78 | ||||||||
| CAS broj | 37211-65-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Polinukleotid 5'-hidroksil-kinaza (EC 2.7.1.78, ATP:5'-defosfopolinukleotid 5'-fosfataza, PNK, polinukleotid 5'-hidroksil kinaza (fosforilacija), 5'-hidroksil polinukleotid kinaza, 5'-hidroksil poliribonukleotid kinaza, 5'-hidroksil RNK kinaza, DNK 5'-hidroksil kinaza, DNK kinaza, polinukleotidna kinaza, polinukleotid 5'-hidroksi-kinaza) je enzim sa sistematskim imenom ATP:5'-defosfopolinukleotid 5'-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim takođe deluje na 5'-defosfo-RNK 3'-mononukleotide.
Reference[uredi | uredi kod]
- ↑ Novogrodsky, A. and Hurwitz, J. (1966). „The enzymatic phosphorylation of ribonucleic acid and deoxyribonucleic acid. I. Phosphorylation at 5′-hydroxyl termini”. J. Biol. Chem. 241: 2923-2932. PMID 4287929.
- ↑ Novogrodsky, A., Tal, M., Traub, A. and Hurwitz, J. (1966). „The enzymatic phosphorylation of ribonucleic acid and deoxyribonucleic acid. II. Further properties of the 5′-hydroxyl polynucleotide kinase”. J. Biol. Chem. 241: 2933-2943. PMID 4287930.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.