Oligo-1,6-glukozidaza
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| Oligo-1,6-glukozidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.2.1.10 | ||||||||
| CAS broj | 9032-15-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Oligo-1,6-glukozidaza (EC 3.2.1.10, izomaltaza, sukraza-izomaltaza, ekso-oligo-1,6-glukozidaza, dekstrin 6alfa-glukanohidrolaza, alfa-limit dekstrinaza, dekstrin 6-glukanohidrolaza, oligosaharid alfa-1,6-glukohidrolaza) je enzim sa sistematskim imenom oligosaharid 6-alfa-glukohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- hidroliza (1->6)-alfa-D-glukozidnih veza u pojedinim oligosaharidima formiranim iz skroba i glikogena enzimom EC 3.2.1.1 (alfa-amilazom), i u izomaltozama
Ovaj enzim, poput EC 3.2.1.33 (amilo-alfa-1,6-glukozidaze), može da odvaja alfa-1->6-vezanu glukozu.
Reference[uredi | uredi kod]
- ↑ Hauri, H.-P., Quaroni, A. and Isselbacher, K.J. (1979). „Biogenesis of intestinal plasma membrane: posttranslational route and cleavage of sucrase-isomaltase”. Proc. Natl. Acad. Sci. USA 76: 5183-5186. PMID 291933.
- ↑ Sjöström, H., Norén, O., Christiansen, L., Wacker, H. and Semenza, G. (1980). „A fully active, two-active-site, single-chain sucrase-isomaltase from pig small intestine. Implications for the biosynthesis of a mammalian integral stalked membrane protein”. J. Biol. Chem. 255: 11332-11338. PMID 7002920.
- ↑ Rodriguez, I.R., Taravel, F.R. and Whelan, W.J. (1984). „Characterization and function of pig intestinal sucrase-isomaltase and its separate subunits”. Eur. J. Biochem. 143: 575-582. PMID 6479163.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.