Nitrit reduktaza (NAD(P)H)
| Nitrit reduktaza (NAD(P)H) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.7.1.4 | ||||||||
| CAS broj | 9029-29-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Nitrit reduktaza (NAD(P)H) (EC 1.7.1.4, nitritna reduktaza (redukovani nikotinamid adenin dinukleotid (fosfat)), NADH-nitritna oksidoreduktaza, NADPH-nitritna reduktaza, asimilatorna nitritna reduktaza, nitritna reduktaza (NAD(P)H2), NAD(P)H2:nitrit oksidoreduktaza) je enzim sa sistematskim imenom amonijum-hidroksid:NAD(P)+ oksidoreduktaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- amonijum hidroksid + 3 NAD(P)+ +H2O nitrit + 3 NAD(P)H + 3 H+
Ovaj enzim je flavoprotein koji sadrži gvožđe-sumpor hem.
- ↑ Cammack, R., Jackson, R.H., Cornish-Bowden, A. and Cole, J.A. (1982). „Electron-spin-resonance studies of the NADH-dependent nitrite reductase from Escherichia coli K12”. Biochem. J. 207: 333-339. PMID 6297458.
- ↑ Lazzarini, R.A. and Atkinson, D.E. (1961). „A triphosphopyridine nucleotide-specific nitrite reductase from Escherichia coli”. J. Biol. Chem. 236: 3330-3335. PMID 14463130.
- ↑ Nicholas, D.J.D., Medina, A. and Jones, O.T.G. (1960). „A nitrite reductase from Neurospora crassa”. Biochim. Biophys. Acta 37: 468-468.
- ↑ Taniguchi, H., Mitsui, H., Nakamura, K. and Egami, F. (1955). „Hydoxylamine reductase”. Ann. Acad. Sci. Fenn. Ser. A II 60: 200-200.
- ↑ Colandene, J.D. and Garrett, R.H. (1996). „Functional dissection and site-directed mutagenesis of the structural gene for NAD(P)H-nitrite reductase in Neurospora crassa”. J. Biol. Chem. 271: 24096-24104. PMID 8798648.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.