NAD+ difosfataza
Izgled
NAD+ difosfataza | |||||||||
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Identifikatori | |||||||||
EC broj | 3.6.1.22 | ||||||||
CAS broj | 37289-33-1 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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NAD+ difosfataza (EC 3.6.1.22, nikotinamid adenin dinukleotidna pirofosfataza, NADP pirofosfataza, NADH pirofosfataza) je enzim sa sistematskim imenom NAD+ fosfohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- NAD+ + H2O AMP + NMN
Ovaj enzim takođe deluje na NADP+, 3-acetilpiridin i na tionikotinamidne analoge molekula NAD+ i NADP+.
- ↑ Anderson, B.M. and Lang, C.A. (1966). „Nicotinamide-adenine dinucleotide pyrophosphatase in the growing and aging mosquito”. Biochem. J. 101: 392-396. PMID 4381708.
- ↑ Nakajima, Y., Fukunaga, N., Sasaki, S. and Usami, S. (1973). „Preparation and properties of NADP pyrophosphatase from Proteus vulgaris”. Biochim. Biophys. Acta 293: 242-255. PMID 4405504.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.