Mutaza
Prijeđi na navigaciju
Prijeđi na pretragu
Mutaza je enzim iz klase izomeraza koji katalizuje prelaz funkcionalne grupe iz jedne pozicije u drugu unutar istog molekula.[1][2] Primeri enzima ove grupe su bisfosfogliceratna mutaza,[3] koja je prisutna u crvenim krvnim zrncima i fosfogliceratna mutaza, koja učestvuje u glikolizi, gde menja 3-fosfoglicerat u 2-fosfoglicerat. Ona menja poziciju fosfatne grupe.
Vidi još[uredi | uredi kod]
Reference[uredi | uredi kod]
- ↑ Donald Voet, Judith G. Voet (2005). Biochemistry (3 izd.). Wiley. ISBN 978-0-471-19350-0.
- ↑ David L. Nelson, Michael M. Cox (2005). Principles of Biochemistry (4th izd.). New York: W. H. Freeman. ISBN 0-7167-4339-6.
- ↑ PDB 1T8P; Wang Y, Wei Z, Bian Q, Cheng Z, Wan M, Liu L, Gong W (September 2004). „Crystal structure of human bisphosphoglycerate mutase”. J. Biol. Chem. 279 (37): 39132–8. DOI:10.1074/jbc.M405982200. PMID 15258155.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.