Monosijalogangliozid sijaliltransferaza
| Monosijalogangliozid sijaliltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.99.2 | ||||||||
| CAS broj | 60202-12-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Monosijalogangliozid sijaliltransferaza (EC 2.4.99.2, CMP-N-acetilneuraminat:D-galaktozil-N-acetil-D-galaktozaminil-(N-acetilneuraminil)-D-galaktozil-D-glukozilkeramid N-acetilneuraminiltransferaza, CMP-N-acetilneuraminat:D-galaktozil-N-acetil-D-galaktozaminil-(N-acetilneuraminil)-D-galaktozil-D-glukozil(1<->1)keramid N-acetilneuraminiltransferaza) je enzim sa sistematskim imenom CMP-N-acetilneuraminat:D-galaktozil-N-acetil-D-galaktozaminil-(N-acetilneuraminil)-D-galaktozil-D-glukozil-(1<->1)-keramid N-acetilneuraminiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- CMP-N-acetilneuraminat + D-galaktozil-N-acetil-D-galaktozaminil-(N-acetilneuraminil)-D-galaktozil-D-glukozil-(1<->1)-keramid CMP + N-acetilneuraminil-D-galaktozil-N-acetil-D-galaktozaminil-(N-acetilneuraminil)-D-galaktozil-D-glukozil-(1<->1)-keramid
Ovaj enzim može da bude identičan sa EC 2.4.99.4, beta-galaktozid alfa-2,3-sijaliltransferazom.
- ↑ Rearick, J.I., Sadler, J.E., Paulson, J.C. and Hill, R.L. (1979). „Enzymatic characterization of β D-galactoside α2→3 sialyltransferase from porcine submaxillary gland”. J. Biol. Chem. 254: 4444-4451. PMID 438198.
- ↑ Yip, M.C.M. (1973). „The enzymic synthesis of disialoganglioside: rat brain cytidine-5′-monophospho-N-acetylneuraminic acid: monosialoganglioside (GM1) sialyltransferase”. Biochim. Biophys. Acta 306: 298-306. PMID 4351506.
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