Limulusni faktor grušavanja C
| Limulusni faktor grušavanja C | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.84 | ||||||||
| CAS broj | 115743-27-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Limulusni faktor grušavanja C (EC 3.4.21.84, faktor C, limulusni faktor C) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Selektivno razlaganje -Arg103-Ser- i -Ile124-Ile- veza u limulusnom faktoru zguršavanja B čime se formira faktor overbar B. Razlaganje -Pro-Arg- veza u sintetičkim supstratima
Ovaj enzim je izolovan iz hemocitnih granula vrsta rakova Limulus i Tachypleus.
- ↑ Nakamura, T., Morita, T. and Iwanaga, S. (1986). „Lipopolysaccharide-sensitive serine-protease zymogen (factor C) found in Limulus hemocytes. Isolation and characterization”. Eur. J. Biochem. 154: 511-521. PMID 3512266.
- ↑ Muta, T., Miyata, T., Misumi, Y., Tokunaga, F., Nakamura, T., Toh, Y., Ikehara, Y. and Iwanaga, S. (1991). „Limulus factor C. An endotoxin-sensitive serine protease zymogen with a mosaic structure of complement-like, epidermal growth factor-like, and lectin-like domains”. J. Biol. Chem. 266: 6554-6561. PMID 2007602.
- ↑ Tokunaga, F., Nakajima, H. and Iwanaga, S. (1991). „Further studies on lipopolysaccharide-sensitive serine protease zymogen (factor C): its isolation from Limulus polyphemus hemocytes and identification as an intracellular zymogen activated by α-chymotrypsin, not by trypsin”. J. Biochem. (Tokyo) 109: 150-157. PMID 2016264.
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