Laktoil-KoA dehidrataza
| Laktoil-KoA dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.54 | ||||||||
| CAS broj | 2604882 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Laktoil-KoA dehidrataza (EC 4.2.1.54, laktoil koenzim A dehidrataza, laktil-koenzim A dehidraza, laktil KoA dehidrataza, akrilil koenzim A hidrataza, laktoil-KoA hidrolijaza) je enzim sa sistematskim imenom (R)-laktoil-KoA hidrolijaza (formira acriloil-KoA).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (R)-laktoil-KoA akriloil-KoA + H2O
Bakterijski enzim učestvuje u propanoatnoj fermentaciji.
- ↑ Baldwin, R.L., Wood, W.A. and Emery, R.S. (1965). „Lactate metabolism by Peptostreptococcus elsdenii: evidence for lactyl coenzyme a dehydrase”. Biochim. Biophys. Acta 97: 202-213. PMID 14292829.
- ↑ Schweiger, G. and Buckel, W. (1984). „On the dehydration of (R)-lactate in the fermentation of alanine to propionate by Clostridium propionicum”. FEBS Lett 171: 79-84. PMID 6586495.
- ↑ Kuchta, R.D. and Abeles, R.H. (1985). „Lactate reduction in Clostridium propionicum. Purification and properties of lactyl-CoA dehydratase”. J. Biol. Chem. 260: 13181-13189. PMID 4055736.
- ↑ Kuchta, R.D., Hanson, G.R., Holmquist, B. and Abeles, R.H. (1986). „Fe-S centers in lactyl-CoA dehydratase”. Biochemistry 25: 7301-7307. PMID 3026450.
- ↑ Hofmeister, A.E. and Buckel, W. (1992). „(R)-lactyl-CoA dehydratase from Clostridium propionicum. Stereochemistry of the dehydration of (R)-2-hydroxybutyryl-CoA to crotonyl-CoA”. Eur. J. Biochem. 206: 547-552. PMID 1597194.
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