L-glukuronat reduktaza
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| L-glukuronat reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.19 | ||||||||
| CAS broj | 9028-29-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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L-glukuronat reduktaza (EC 1.1.1.19, L-glukuronatna reduktaza, aldehid reduktaza, L-heksonat:NADP dehidrogenaza, TPN-L-gulonat dehidrogenaza, aldehid reduktaza II, NADP-L-gulonat dehidrogenaza, D-glukuronat dehidrogenaza, D-glukuronat reduktaza) je enzim sa sistematskim imenom L-gulonat:NADP+ 6-oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-gulonat + NADP+ D-glukuronat + NADPH + H+
Takođe redukuje D-galakturonat. Može da bude identičan sa EC 1.1.1.2 (alkohol dehidrogenazom (NADP+)).
Reference[uredi | uredi kod]
- ↑ Sivak, A. and Hoffmann-Ostenhof, O. (1961). „Enzymes of meso-inositol catabolism in the yeast Schwanniomyces occidentalis”. Biochim. Biophys. Acta 53: 426-428. PMID 13913518.
- ↑ von Wartburg, J.P. and Wermoth, B. (1980). „Aldehyde reductase”. u: Jakoby, W.B.. Enzymatic Basis of Detoxication. 1. New York: Academic Press. str. 249-260.
- ↑ York, J.L., Grollman, A.P. and Bublitz, C. (1961). „TPN-L-gulonate dehydrogenase”. Biochim. Biophys. Acta 47: 298-306. PMID 13787380.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.