Kortizon a-reduktaza
Prijeđi na navigaciju
Prijeđi na pretragu
| Kortizon a-reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.4 | ||||||||
| CAS broj | 2604066 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Kortizon a-reduktaza (EC 1.3.1.4, kortizonska Delta4-5alfa-reduktaza, mikrozomalna steroidna reduktaza (5alfa), Delta4-3-ketosteroidna reduktaza (5alfa), Delta4-3-oksosteroid-5alfa-reduktaza, NADPH:Delta4-3-oksosteroid-5alfa-oksidoreduktaza, Delta4-5alfa-reduktaza) je enzim sa sistematskim imenom 4,5alfa-dihidrokortizon:NADP+ Delta4-oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 4,5alfa-dihidrokortizon + NADP+ kortizon + NADPH + H+
Reference[uredi | uredi kod]
- ↑ McGuire, J.S., Hollis, V.W. and Tomkins, G.M. (1960). „Some characteristics of the microsomal steroid reductases (5alpha) of rat liver”. J. Biol. Chem. 235: 3112-3117.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.