Kinaza receptora za lipoprotein niske gustine
| Kinaza receptora za lipoprotein niske gustine | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.11.29 | ||||||||
| CAS broj | 107445-00-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Kinaza receptora za lipoprotein niske gustine (EC 2.7.11.29, ATP:lipoprotein niske gustine L-serin O-fosfotransferaza, LDL receptorska kinaza, (lipoprotein niske gustine) kinaza, kinaza lipoproteina niske gustine, receptorska kinaza lipoproteina niske gustine (fosforilacija), STK7) je enzim sa sistematskim imenom ATP:(receptor lipoproteina niske gustine)-L-serin O-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + [receptor lipoprotein niske gustine]-L-serin ADP + [receptor lipoprotein niske gustine]-O-fosfo-L-serin
Ovaj enzim fosforiliše zadnji serinski ostatak (Ser-833) u citoplazmičnom domenu receptora lipoproteina niske gustine iz goveđeg adrenalnog korteksa.
- ↑ Kishimoto, A., Brown, M.S., Slaughter, C.A. and Goldstein, J.L. (1987). „Phosphorylation of serine 833 in cytoplasmic domain of low density lipoprotein receptor by a high molecular weight enzyme resembling casein kinase II”. J. Biol. Chem. 262: 1344-1351. PMID 3100530.
- ↑ Kishimoto, A., Goldstein, J.L. and Brown, M.S. (1987). „Purification of catalytic subunit of low density lipoprotein receptor kinase and identification of heat-stable activator protein”. J. Biol. Chem. 262: 9367-9373. PMID 3597414.
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