Katehol 1,2-dioksigenaza
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| Katehol 1,2-dioksigenaza | |||||||||
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| Katehol 1,2-dioksigenaza homodimer, Burkholderia ambifaria | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.13.11.1 | ||||||||
| CAS broj | 9027-16-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Katehol 1,2-dioksigenaza (EC 1.13.11.1, katehol-kiseonik 1,2-oksidoreduktaza, 1,2-pirokatehaza, katehaza, katehol 1,2-oksigenaza, katehol dioksigenaza, pirokatehaza, pirokatehol 1,2-dioksigenaza, CD I, CD II) je enzim sa sistematskim imenom katehol:kiseonik 1,2-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- katehol + O2 cis,cis-mukonat
Za rad ovog enzima neohodan je Fe3+. On učestvuje u metabolizmu nitro-aromatičnih jedinjenja kod vrsta Pseudomonas putida.
Reference[uredi | uredi kod]
- ↑ Hayaishi, O. (1963). „Direct oxygenation by O2, oxygenases”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 8 (2nd izd.). New York: Academic Press. str. 353-371.
- ↑ Hayaishi, O., Katagiri, M. and Rothberg, S. (1957). „Studies on oxygenases: pyrocatechase.”. J. Biol. Chem. 229: 905-920. PMID 13502352.
- ↑ Sistrom, W.R. and Stanier, R.Y. (1954). „The mechanism of formation of β-ketoadipic acid by bacteria”. J. Biol. Chem. 210: 821-836. PMID 13211620.
- ↑ Zeyer, J., Kocher, H.P. and Timmis, N. (1986). „Influence of para-substituents on the oxidative metabolism of o-nitrophenols by Pseudomonas putida B2”. Appl. Environ. Microbiol. 52: 334-339. PMID 3752997.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.