Inozitol-trisfosfat 3-kinaza
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| Inozitol-trisfosfat 3-kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.1.127 | ||||||||
| CAS broj | 106283-10-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Inozitol-trisfosfat 3-kinaza (EC 2.7.1.127, 1D-mio-inozitol-trisfosfat 3-kinaza, Ins(1,4,5)P3 3-kinaza) je enzim sa sistematskim imenom ATP:1D-mio-inozitol-1,4,5-trisfosfat 3-fosfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim se aktivira jonom Ca2+. Poznate su tri izoforme.
Reference[uredi | uredi kod]
- ↑ Hansen, C.A., Mah, S. and Williamson, J.R. (1986). „Formation and metabolism of inositol 1,3,4,5-tetrakisphosphate in liver”. J. Biol. Chem. 261: 8100-8103. PMID 3487541.
- ↑ Irvine, R.F., Letcher, A.J., Heslop, J.P. and Berridge, M.J. (1986). „The inositol tris/tetrakisphosphate pathway - demonstration of Ins(1,4,5)P3 3-kinase activity in animal tissues”. Nature 320: 631-634. PMID 3010126.
- ↑ Irvine, R.F. and Schell, M.J. (2001). „Back in the water - the return of the inositol phosphates”. Nat. Rev. Mol. Cell. Biol. 2: 327-338. PMID 11331907.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.