Hondroitinska ABC lijaza
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| Hondroitinska ABC lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.2.4 | ||||||||
| CAS broj | 9024-13-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Hondroitinska ABC lijaza (EC 4.2.2.4, hondroitinaza, hondroitin ABC eliminaza, hondroitinaza ABC, hondroitin ABC lijaza) je enzim sa sistematskim imenom hondroitin ABC lijaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Eliminativa degradacija polisaharida koji sadrže 1,4-beta-D-heksozaminil i 1,3-beta-D-glukuronazil ili 1,3-alfa-L-iduronozil veze do disaharida koji sadrže 4-dezoksi-beta-D-gluk-4-enuronozil grupe
Ovaj enzim deluje hondroitin 4-sulfat, hondroitin 6-sulfat i dermatan sulfat.
Reference[uredi | uredi kod]
- ↑ Yamagata, T., Saito, H., Habuchi, O. and Suzuki, S. (1968). „Purification and properties of bacterial chondroitinases and chondrosulfatases”. J. Biol. Chem. 243: 1523-1535. PMID 5647268.
- ↑ Saito, H., Yamagata, T. and Suzuki, S. (1968). „Enzymatic methods for the determination of small quantities of isomeric chondroitin sulfates”. J. Biol. Chem. 243: 1536-1542. PMID 4231029.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.