Hondro-4-sulfataza
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| Hondro-4-sulfataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.6.9 | ||||||||
| CAS broj | 9045-75-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Hondro-4-sulfataza (EC 3.1.6.9, hondroitin-4-sulfataza, 4-dezoksi-beta-D-gluk-4-enuronozil-(1,3)-N-acetil-D-galaktozamin-4-sulfat 4-sulfohidrolaza) je enzim sa sistematskim imenom 4-dezoksi-beta-D-gluk-4-enuronozil-(1->3)-N-acetil-D-galaktozamin-4-sulfat 4-sulfohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 4-dezoksi-beta-D-gluk-4-enuronozil-(1->3)-N-acetil-D-galaktozamin 4-sulfat + H2O 4-dezoksi-beta-D-gluk-4-enuronozil-(1->3)-N-acetil-D-galaktozamin + sulfat
Ovaj enzim takođe deluje na zasićene analoge.
Reference[uredi | uredi kod]
- ↑ Held, V.E. and Buddecke, E. (1967). „Nachweis, Reinigung und Eigenschaften einer Chondroitin-4-Sulfatase aus der Aorta des Rindes”. Hoppe-Seyler's Z. Physiol. Chem. 348: 1047-1060. PMID 5595107.
- ↑ Roy, A.B. (1976). „Sulphatases, lysosomes and disease”. Aust. J. Exp. Biol. Med. Sci. 54: 111-135. PMID 13772.
- ↑ Yamagata, T., Saito, H., Habuchi, O. and Suzuki, S. (1968). „Purification and properties of bacterial chondroitinases and chondrosulfatases”. J. Biol. Chem. 243: 1523-1535. PMID 5647268.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.