Gvanidinoacetat N-metiltransferaza
| Gvanidinoacetat N-metiltransferaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 2.1.1.2 | ||||||||
| CAS broj | 9029-75-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Gvanidinoacetat N-metiltransferaza (EC 2.1.1.2, GA metilferaza, gvanidinoacetatna metiltransferaza, gvanidinoacetatna transmetilaza, metionin-gvanidinoacetilna transmetilaza, gvanidoacetatna metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:N-gvanidinoacetat metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + gvanidinoacetat S-adenozil-L-homocistein + kreatin
- ↑ Cantoni, G.L. and Scarano, E. (1954). „The formation of S-adenosylhomocysteine in enzymatic transmethylation reactions”. J. Am. Chem. Soc. 76: 4744-4744.
- ↑ Cantoni, G.L. and Vignos, P.J. (1954). „Enzymatic mechanism of creatine synthesis”. J. Biol. Chem. 209: 647-659. PMID 13192118.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.