Guanilat kinaza

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Guanilat kinaza
Identifikatori
EC broj 2.7.4.8
CAS broj 9026-59-9
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Guanilat kinaza (EC 2.7.4.8, dezoksiguanilatna kinaza, 5'-GMP kinaza, GMP kinaza, guanozin monofosfatna kinaza, ATP:GMP fosfotransferaza) je enzim sa sistematskim imenom ATP:(d)GMP fosfotransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + GMP ADP + GDP

dGMP takođe deluje kao akceptor, dok dATP može da bude donor.

Reference[uredi | uredi kod]

  1. Buccino, R.J., Jr. and Roth, J.S. (1969). „Partial purification and properties of ATP:GMP phosphotransferase from rat liver”. Arch. Biochem. Biophys. 132: 49-61. PMID 4307347. 
  2. Hiraga, S. and Sugino, Y. (1966). „Nucleoside monophosphokinases of Escherichia coli infected and uninfected with an RNA phage”. Biochim. Biophys. Acta 114: 416-418. PMID 5329274. 
  3. Griffith, T.J. and Helleiner, C.W. (1965). „The partial purification of deoxynucleoside monophosphate kinases from L cells”. Biochim. Biophys. Acta 108: 114-124. PMID 5862227. 
  4. Oeschger, M.P. and Bessman, M.J. (1966). „Purification and properties of guanylate kinase from Escherichia coli”. J. Biol. Chem. 241: 5452-5460. PMID 5333666. 
  5. Shimono, H. and Sugino, Y. (1971). „Metabolism of deoxyribonucleotides. Purification and properties of deoxyguanosine monophosphokinase of calf thymus”. Eur. J. Biochem. 19: 256-263. PMID 5552394. 

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