Glutamat formiminotransferaza
Izgled
Glutamat formiminotransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.1.2.5 | ||||||||
CAS broj | 9032-83-1 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Glutamat formiminotransferaza (EC 2.1.2.5, glutamatna formiltransferaza, formiminoglutaminsko kiselinska transferaza, formiminoglutaminska formiminotransferaza, glutamatna formiminotransferaza) je enzim sa sistematskim imenom 5-formimidoiltetrahidrofolat:L-glutamat N-formimidoiltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 5-formimidoiltetrahidrofolat + L-glutamat tetrahidrofolat + N-formimidoil-L-glutamat
Ovaj enzim je piridoksal-fosfatni protein. On takođe katalizuje formilni transfer sa 5-formiltetrahidrofolata na L-glutamat.
- ↑ Miller, A. and Waelsch, H. (1957). „Formimino transfer from formamidinoglutaric acid to tetrahydrofolic acid”. J. Biol. Chem. 228: 397-417. PMID 13475327.
- ↑ Silverman, M., Keresztesy, J.C., Koval, G.J. and Gardiner, R.C. (1957). „Citrovorium factor and the synthesis of formylglutamic acid”. J. Biol. Chem. 226: 83-94. PMID 13428739.
- ↑ Tabor, H. and Wyngarden, L. (1959). „The enzymatic formation of formiminotetrahydrofolic acid, 5,10-methenyltetrahydrofolic acid, and 10-formyltetrahydrofolic acid in the metabolism of formiminoglutamic acid”. J. Biol. Chem. 234: 1830-1849. PMID 13672973.
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