Glicerol-3-fosfat dehidrogenaza (NAD(P)+)
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| Glicerol-3-fosfat dehidrogenaza (NAD(P)+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.94 | ||||||||
| CAS broj | 37250-30-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Glicerol-3-fosfat dehidrogenaza (NAD(P)+) (EC 1.1.1.94, L-glicerol-3-fosfat:NAD(P) oksidoreduktaza, glicerol fosfat dehidrogenaza (nikotinamid adenin dinukleotid (fosfat)), glicerol 3-fosfat dehidrogenaza (NADP), glicerol-3-fosfat dehidrogenaza (NAD(P))) je enzim sa sistematskim imenom sn-glicerol-3-fosfat:NAD(P)+ 2-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- sn-glicerol 3-fosfat + NAD(P)+ gliceron fosfat + NAD(P)H + H+
Ovaj enzim iz Escherichia coli manifestuje specifičnost za B stranu NADPH.
Reference[uredi | uredi kod]
- ↑ Kito, M. and Pizer, L.I. (1969). „Purification and regulatory properties of the biosynthetic L-glycerol 3-phosphate dehydrogenase from Escherichia coli”. J. Biol. Chem. 244: 3316-3323. PMID 4389388.
- ↑ Edgar, J.R. and Bell, R.M. (1978). „Biosynthesis in Escherichia coli of sn-glycerol 3-phosphate, a precursor of phospholipid”. J. Biol. Chem. 253: 6348-6353. PMID 355254.
- ↑ Edgar, J.R. and Bell, R.M. (1978). „Biosynthesis in Escherichia coli of sn-glycerol 3-phosphate, a precursor of phospholipid. Kinetic characterization of wild type and feedback-resistant forms of the biosynthetic sn-glycerol-3-phosphate dehydrogenase”. J. Biol. Chem. 253: 6354-6363. PMID 28326.
- ↑ Edgar, J.R. and Bell, R.M. (1980). „Biosynthesis in Escherichia coli of sn-glycerol-3-phosphate, a precursor of phospholipid. Further kinetic characterization of wild type and feedback-resistant forms of the biosynthetic sn-glycerol-3-phosphate dehydrogenase”. J. Biol. Chem. 255: 3492-3497. PMID 6767719.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.