Fosfoglukozaminska mutaza
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Fosfoglukozaminska mutaza | |||||||||
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Identifikatori | |||||||||
EC broj | 5.4.2.10 | ||||||||
CAS broj | 9031-92-9 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Fosfoglukozaminska mutaza (EC 5.4.2.10, Phosphoglucosamine mutase) je enzim sa sistematskim imenom alfa-D-glukozamin 1,6-fosfomutaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- alfa-D-glukozamin 1-fosfat D-glukozamin 6-fosfat
Ovaj enzim učestvuje u biosintezi peptidoglikana i lipopolisaharida bakterijskog ćelijskog zida.
Reference[uredi | uredi kod]
- ↑ Mengin-Lecreulx, D. and van Heijenoort, J. (1996). „Characterization of the essential gene glmM encoding phosphoglucosamine mutase in Escherichia coli”. J. Biol. Chem. 271: 32-39. PMID 8550580.
- ↑ de Reuse, H., Labigne, A. and Mengin-Lecreulx, D. (1997). „The Helicobacter pylori ureC gene codes for a phosphoglucosamine mutase”. J. Bacteriol. 179: 3488-3493. PMID 9171391.
- ↑ Jolly, L., Wu, S., van Heijenoort, J., de Lencastre, H., Mengin-Lecreulx, D. and Tomas, A. (1997). „The femR315 gene from Staphylococcus aureus', the interruption of which results in reduced methicillin resistance, encodes a phosphoglucosamine mutase”. J. Bacteriol. 179: 5321-5325. PMID 9286983.
- ↑ Jolly, L., Ferrari, P., Blanot, D., van Heijenoort, J., Fassy, F. and Mengin-Lecreulx, D. (1999). „Reaction mechanism of phosphoglucosamine mutase from Escherichia coli”. Eur. J. Biochem. 262: 202-210. PMID 10231382.
- ↑ Jolly, L., Pompeo, F., van Heijenoort, J., Fassy, F. and Mengin-Lecreulx, D. (2000). „Autophosphorylation of phosphoglucosamine mutase from Escherichia coli”. J. Bacteriol. 182: 1280-1285. PMID 10671448.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.