Fosfatidilholin 12-monooksigenaza
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| Fosfatidilholin 12-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.26 | ||||||||
| CAS broj | 77950-95-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Fosfatidilholin 12-monooksigenaza (EC 1.14.13.26, ricinoleinska kiselina sintaza, oleatna Delta12-hidroksilaza, oleatna Delta12-monooksigenaza) je enzim sa sistematskim imenom 1-acil-2-oleoil-sn-glicero-3-fosfoholin,NADH:kiseonik oksidoreduktaza (12-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 1-acil-2-oleoil-sn-glicero-3-fosfoholin + NADH + H+ + O2 1-acil-2-[(S)-12-hidroksioleoil]-sn-glicero-3-fosfoholin + NAD+ + H2O
Reference[uredi | uredi kod]
- ↑ Galliard, T. and Stumpf, P.K. (1966). „Fat metabolism in higher plants. 30. Enzymatic synthesis of ricinoleic acid by a microsomal preparation from developing Ricinus communis seeds”. J. Biol. Chem. 241: 5806-5812. PMID 4289003.
- ↑ Moreau, R.A. and Stumpf, P.K. (1981). „Recent studies of the enzymic-synthesis of ricinoleic acid by developing castor beans”. Plant Physiol. 67: 672-676. PMID 16661734.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.