Format-tetrahidrofolatna ligaza
| Format-tetrahidrofolatna ligaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 6.3.4.3 | ||||||||
| CAS broj | 9023-66-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Format-tetrahidrofolatna ligaza (EC 6.3.4.3, formiltetrahidrofolatna sintetaza, 10-formiltetrahidrofolatna sintetaza, tetrahidrofolna formilaza, tetrahidrofolatna formilaza) je enzim sa sistematskim imenom format:tetrahidrofolat ligaza (formira ADP).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + format + tetrahidrofolat ADP + fosfat + 10-formiltetrahidrofolat
Kod eukariota se javlja trifunkcionalni enzim.
- ↑ Jaenicke, L. and Brode, E. (1961). „Untersuchungen über Einkohlenstoffkörper. I. Die Tetrahydrofolatformylase aus Taubenleber. Rinigung und Mechanismus”. Biochem. Z. 334: 108-132. PMID 13789141.
- ↑ Long, C.W., Levitzki, A., Houston, L.L and Koshland, D.E., Jr. (1969). „Subunit structures and interactions of CTP synthetase”. Fed. Proc. 28: 342-342.
- ↑ Rabinowitz, J.C. and Pricer, W.E. (1962). „Formyltetrahydrofolate synthetase. I. Isolation and crystallization of the enzyme”. J. Biol. Chem. 237: 2898-2902. PMID 14489619.
- ↑ Whiteley, H.R., Osborn, M.J. and Huennekens, F.M. (1959). „Purification and properties of the formate-activating enzyme from Micrococcus aerogenes”. J. Biol. Chem. 234: 1538-1543. PMID 13654413.
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