Formaldehid transketolaza
| Formaldehid transketolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.2.1.3 | ||||||||
| CAS broj | 124566-23-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Formaldehid transketolaza (EC 2.2.1.3, dihidroksiacetonska sintaza) je enzim sa sistematskim imenom D-ksiluloza-5-fosfat:formaldehid glikolaldehidtransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-ksiluloza 5-fosfat + formaldehid gliceraldehid 3-fosfat + gliceron
Ovaj enzim je tiamin-difosfatni protein. On nije identical sa EC 2.2.1.1, transketolazom. Ovaj enzim takođe konvertuje hidroksipiruvat i formaldehid u gliceron i CO2.
- ↑ Bystrykh, L.V., Sokolov, A.P. and Trotsenko, Yu.A. (1981). „Separation of transketolase and dihydroxyacetone synthase from methylotrophic yeasts”. Dokl. Akad. Nauk SSSR. 258: 499-501. PMID 7249920.
- ↑ Kato, N., Higuchi, T., Sakazawa, C., Nishizawa, T., Tani, Y. and Yamada, H. (1982). „Purification and properties of a transketolase responsible for formaldehyde fixation in a methanol-utilizing yeast, Candida boidinii (Kloeckera sp.) No. 2201”. Biochim. Biophys. Acta 715: 143-150. PMID 7074134.
- ↑ Waites, M.J. and Quayle, J.R. (1981). „The interrelation between transketolase and dihydroxyacetone synthase activities in the methylotrophic yeast Candida boidinii”. J. Gen. Microbiol. 124: 309-316. PMID 6276498.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.