Lipopolisaharid glukoziltransferaza I
(Preusmjereno sa stranice EC 2.4.1.58)
| Lipopolisaharid glukoziltransferaza I | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.58 | ||||||||
| CAS broj | 9074-00-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Lipopolisaharid glukoziltransferaza I (EC 2.4.1.58, UDP-glukoza:lipopolisaharid glukoziltransferaza I, lipopolisaharid glukoziltransferaza, uridin difosfat glukoza:lipopolisaharid glukoziltransferaza I, uridin difosfoglukoza-lipopolisaharid glukoziltransferaza) je enzim sa sistematskim imenom UDP-glukoza:lipopolisaharid glukoziltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-glukoza + lipopolisaharid UDP + D-glukozil-lipopolisaharid
Prenosi glukozilne ostatke na osnovu lipopolisaharida, cf. EC 2.4.1.44 (lipopolisaharid 3-alfa-galaktoziltransferaza, EC 2.4.1.56 (lipopolisaharid N-acetilglukozaminiltransferaza) i EC 2.4.1.73 (lipopolisaharid glukoziltransferaza II).
Reference[uredi | uredi kod]
- ↑ Müller, E., Hinckley, A. and Rothfield, L. (1972). „Studies of phospholipid-requiring bacterial enzymes. 3. Purification and properties of uridine diphosphate glucose:lipopolysaccharide glucosyltransferase I”. J. Biol. Chem. 247: 2614-2622. PMID 4553445.
- ↑ Rothfield, L., Osborn, M.J. and Horecker, B.L. (1964). „Biosynthesis of bacterial lipopolysaccharide. II. Incorporation of glucose and galactose catalyzed by particulate and soluble enzymes in salmonella”. J. Biol. Chem. 239: 2788-2795. PMID 14217875.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.