Sorbozna reduktaza
(Preusmjereno sa stranice EC 1.1.1.289)
| Sorbozna reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.289 | ||||||||
| CAS broj | 138440-90-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Sorbozna reduktaza (EC 1.1.1.289, Sou1p) je enzim sa sistematskim imenom D-glucitol:NADP+ oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-glucitol + NADP+ L-sorboza + NADPH + H+
Reakcija se predominantno odvija u reverznom smeru. Ovaj enzim takođe može da konvertuje D-fruktozu u D-manitol, ali sa manjom brzinom. Sorbozna reduktaza pripada familiji dehidrogenaza kratkog lanca.
Reference[uredi | uredi kod]
- ↑ Greenberg, J.R., Price, N.P., Oliver, R.P., Sherman, F. and Rustchenko, E. (2005). „Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization”. Yeast 22: 957-969. PMID 16134116.
- ↑ Greenberg, J.R., Price, N.P., Oliver, R.P., Sherman, F. and Rustchenko, E. (2005). „Erratum report: Candida albicans SOU1 encodes a sorbose reductase required for L-sorbose utilization”. Yeast 22: 1171-1171.
- ↑ Sugisawa, T., Hoshino, T. and Fujiwara, A. (1991). „Purification and properties of NADPH-linked L-sorbose reductase from Gluconobacter melanogenus N44-1”. Agric. Biol. Chem. 55: 2043-2049.
- ↑ Shinjoh, M., Tazoe, M. and Hoshino, T. (2002). „NADPH-dependent L-sorbose reductase is responsible for L-sorbose assimilation in Gluconobacter suboxydans IFO 3291”. J. Bacteriol. 184: 861-863. PMID 11790761.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.