Dugolančana-masna-acil-KoA reduktaza
| Dugolančana-masna-acil-KoA reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.2.1.50 | ||||||||
| CAS broj | 50936-56-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Dugolančana-masna-acil-KoA reduktaza (EC 1.2.1.50, acil-KoA reduktaza, acil koenzim A reduktaza) je enzim sa sistematskim imenom dugolančani aldehid:NADP+ oksidoreduktaza (formira acil-KoA).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- dugolančani aldehid + KoA + NADP+ dugolančani acil-KoA + NADPH + H+
Zajedno sa EC 6.2.1.19, ligazom dugolančane masne-kiseline---luciferin-komponente, formira reduktazni sistem masnih kiselina koji formura supstrat za EC 1.14.14.3, alkanalnu monooksigenazu (FMN-vezanu). Ona je deo bakterijskog luciferaznog sistema.
- ↑ Riendeau, D., Rodrigues, A. and Meighen, E. (1982). „Resolution of the fatty acid reductase from Photobacterium phosphoreum into acyl protein synthetase and acyl-CoA reductase activities. Evidence for an enzyme complex”. J. Biol. Chem. 257: 6908-6915. PMID 7085612.
- ↑ Wall, L. and Meighen, E.A. (1986). „Subunit structure of the fatty-acid reductase complex from Photobacterium phosphoreum”. Biochemistry 25: 4315-4321.
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