Dolihil-fosfat b-glukoziltransferaza
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Dolihil-fosfat b-glukoziltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.4.1.117 | ||||||||
CAS broj | 71061-42-2 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Dolihil-fosfat b-glukoziltransferaza (EC 2.4.1.117, poliprenil fosfat:UDP-D-glukoza glukoziltransferaza, UDP-glukoza dolihil-fosfat glukoziltransferaza, uridin difosfoglukoza-dolihol glukoziltransferaza, UDP-glukoza:dolihol fosfat glukoziltransferaza, UDP-glukoza:doliholfosforil glukoziltransferaza, UDP-glukoza:dolihil monofosfat glukoziltransferaza, UDP-glukoza:dolihil fosfat glukoziltransferaza) je enzim sa sistematskim imenom UDP-glukoza:dolihil-fosfat beta-D-glukoziltransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-glukoza + dolihil fosfat UDP + dolihil beta-D-glukozil fosfat
Solanezil fosfat i fikaprenil fosfat mogu da budu akceptori.
Reference[uredi | uredi kod]
- ↑ Behrens, N.H. and Leloir, L.F. (1970). „Dolichol monophosphate glucose: an intermediate in glucose transfer in liver”. Proc. Natl Acad. Sci. USA 66: 153-159. PMID 5273893.
- ↑ Herscovics, A., Bugge, B. and Jeanloz, R.W. (1977). „Glucosyltransferase activity in calf pancreas microsomes. Formation of dolichyl D[14C]glucosyl phosphate and 14C-labeled lipid-linked oligosaccharides from UDP-D-[14C]glucose”. J. Biol. Chem. 252: 2271-2277. PMID 849929.
- ↑ Villemez, C.L. and Carlo, P.L. (1979). „Properties of a soluble polyprenyl phosphate: UDP-D-glucose glucosyltransferase”. J. Biol. Chem. 254: 4814-4819. PMID 438216.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.