Dolihil-fosfat a-N-acetilglukozaminiltransferaza
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| Dolihil-fosfat a-N-acetilglukozaminiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.1.153 | ||||||||
| CAS broj | 63363-73-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Dolihil-fosfat a-N-acetilglukozaminiltransferaza (EC 2.4.1.153, uridin difosfoacetilglukozamin-dolihol fosfatna acetilglukozaminiltransferaza, dolihil fosfatna acetilglukozaminiltransferaza, dolihil fosfatna N-acetilglukozaminiltransferaza, UDP-N-acetilglukozamin-dolihol fosfatna N-acetilglukozaminiltransferaza) je enzim sa sistematskim imenom UDP-N-acetil-D-glukozamin:dolihil-fosfat alfa-N-acetil-D-glukozaminiltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-N-acetil-D-glukozamin + dolihil fosfat UDP + dolihil N-acetil-alfa-D-glukozaminil fosfat
Reference[uredi | uredi kod]
- ↑ Leloir, L.F., Staneloni, R.J., Carminatti, H. and Behrens, N.H. (1973). „The biosynthesis of a N,N'-diacetylchitobiose containing lipid by liver microsomes. A probable dolichol pyrophosphate derivative”. Biochem. Biophys. Res. Commun. 52: 1285-1292. PMID 4717748.
- ↑ Molnar, J., Chao, H. and Ikehara, Y. (1971). „Phosphoryl-N-acetylglucosamine transfer to a lipid acceptor of liver microsomal preparations”. Biochim. Biophys. Acta 239: 401-410. PMID 5113503.
- ↑ Tetas, M., Chao, H. and Molnar, J. (1970). „Incorporation of carbohydrates into endogenous acceptors of liver microsomal fractions”. Arch. Biochem. Biophys. 138: 135-146. PMID 4315690.
- ↑ Warren, C.D. and Jeanloz, R.W. (1974). „Chemical synthesis of P1-2-acetamido-2-deoxy-α-D-glucopyranosyl P2-dolichyl pyrophosphate”. Carbohydr. Res. 37: 252-260. PMID 4371972.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.