Dihidropteroat sintaza
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| Dihidropteroat sintaza | |||||||||
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| Dihidropteroat sintaza homodimer, Bacillus anthracis | |||||||||
| Identifikatori | |||||||||
| EC broj | 2.5.1.15 | ||||||||
| CAS broj | 9055-61-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Dihidropteroat sintaza (EC 2.5.1.15, dihidropteroat pirofosforilaza, DHPS, 7,8-dihidropteroat sintaza, 7,8-dihidropteroat sintetaza, 7,8-dihidropteroinska kiselina sintetaza, dihidropteroat sintetaza, dihidropteroinska sintetaza, 2-amino-4-hidroksi-6-hidroksimetil-7,8-dihidropteridin-difosfat:4-aminobenzoat 2-amino-4-hidroksidihidropteridin-6-meteniltransferaza) je enzim sa sistematskim imenom (2-amino-4-hidroksi-7,8-dihidropteridin-6-il)metil-difosfat:4-aminobenzoat 2-amino-4-hidroksidihidropteridin-6-meteniltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (2-amino-4-hidroksi-7,8-dihidropteridin-6-il)metil difosfat + 4-aminobenzoat difosfat + 7,8-dihidropteroat
Reference[uredi | uredi kôd]
- ↑ Richey, D.P. and Brown, G.M. (1969). „The biosynthesis of folic acid. IX. Purification and properties of the enzymes required for the formation of dihydropteroic acid”. J. Biol. Chem. 244: 1582-1592. PMID 4304228.
- ↑ Shiota, T., Baugh, C.M., Jackson, R. and Dillard, R. (1969). „The enzymatic synthesis of hydroxymethyldihydropteridine pyrophosphate and dihydrofolate”. Biochemistry 8: 5022-5028. PMID 4312465.
Literatura[uredi | uredi kôd]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. http://books.google.com/books/about/Fundamentals_of_enzymology.html?id=8uvwAAAAMAAJ.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. http://books.google.com/books/about/Advances_in_Enzymology_and_Related_Areas.html?id=Pmh8yToeuloC.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. http://www.garlandscience.com/textbooks/0815323042.asp?type=reviews.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. http://books.google.com/books/about/Enzyme_Kinetics.html?id=T60oAAAAYAAJ.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. http://books.google.com/books/about/Evaluation_of_Enzyme_Inhibitors_in_Drug.html?id=l2rMy8QNUk0C.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. http://books.google.com/books/about/Biochemical_pathways.html?id=081qAAAAMAAJ.
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