Dihidrolipoil dehidrogenaza
Idi na navigaciju
Idi na pretragu
| Dihidrolipoil dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Dihidrolipoil dehidrogenaza dimer, Pseudomonas putida | |||||||||
| Identifikatori | |||||||||
| EC broj | 1.8.1.4 | ||||||||
| CAS broj | 9001-18-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Dihidrolipoil dehidrogenaza (EC 1.8.1.4, LDP-Glc, LDP-Val, dehidrolipoatna dehidrogenaza, dijaforaza, dihidrolipoamidna dehidrogenaza, dihidrolipoamid:NAD+ oksidoreduktaza, dihidrolipoinska dehidrogenaza, dihidrotioktinska dehidrogenaza, lipoamidna dehidrogenaza (NADH), lipoamidna oksidoreduktaza (NADH), lipoamidna reduktaza, lipoamidna reduktaza (NADH), lipoatna dehidrogenaza, lipoinsko kiselinska dehidrogenaza, lipoilna dehidrogenaza, protein-6-N-(dihidrolipoil)lizin:NAD+ oksidoreduktaza) je enzim sa sistematskim imenom protein-N6-(dihidrolipoil)lizin:NAD+ oksidoreduktaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- protein N6-(dihidrolipoil)lizin + NAD+ protein N6-(lipoil)lizin + NADH + H+
Ovaj enzim je flavoprotein (FAD). On je komponenta multienzimskog kompleksa 2-okso-kiselinske dehidrogenaze.
Reference[uredi - уреди | uredi kôd]
- ↑ Massey, V. (1963). „Lipoyl dehydrogenase”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 7 (2nd izd.). New York: Academic Press. str. 275-306.
- ↑ Massey, V., Gibson, Q.H. and Veeger, C. (1960). „Intermediates in the catalytic action of lipoyl dehydrogenase (diaphorase)”. Biochem. J. 77: 341-351. PMID 13767908.
- ↑ Savage, N. (1957). „Preparation and properties of highly purified diaphorase”. Biochem. J. 67: 146-155. PMID 13471525.
- ↑ Straub, F.B. (1939). „Isolation and properties of a flavoprotein from heart muscle tissue”. Biochem. J. 33: 787-792. PMID 16746974.
- ↑ Perham, R.N. (2000). „Swinging arms and swinging domains in multifunctional enzymes: catalytic machines for multistep reactions”. Annu. Rev. Biochem. 69: 961-1004. PMID 10966480.
- ↑ Nesbitt, N.M., Baleanu-Gogonea, C., Cicchillo, R.M., Goodson, K., Iwig, D.F., Broadwater, J.A., Haas, J.A., Fox, B.G. and Booker, S.J. (2005). „Expression, purification, and physical characterization of Escherichia coli lipoyl(octanoyl)transferase”. Protein Expr. Purif. 39: 269-282. PMID 15642479.
Literatura[uredi - уреди | uredi kôd]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. http://books.google.com/books/about/Fundamentals_of_enzymology.html?id=8uvwAAAAMAAJ.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. http://books.google.com/books/about/Advances_in_Enzymology_and_Related_Areas.html?id=Pmh8yToeuloC.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. http://www.garlandscience.com/textbooks/0815323042.asp?type=reviews.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. http://books.google.com/books/about/Enzyme_Kinetics.html?id=T60oAAAAYAAJ.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. http://books.google.com/books/about/Evaluation_of_Enzyme_Inhibitors_in_Drug.html?id=l2rMy8QNUk0C.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. http://books.google.com/books/about/Biochemical_pathways.html?id=081qAAAAMAAJ.
Spoljašnje veze[uredi - уреди | uredi kôd]
| ||||||||||||||