Diadenozin heksafosfatna hidrolaza (formira ATP)
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| Diadenozin heksafosfatna hidrolaza (formira ATP) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.1.61 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Diadenozin heksafosfatna hidrolaza (formira ATP) (EC 3.6.1.61, Ndx1) je enzim sa sistematskim imenom P1,P6-bis(5'-adenozil)heksafosfat nukleotidohidrolaza (formira ATP).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (1) P1,P6-bis(5'-adenozil)heksafosfat + H2O 2 ATP
- (2) P1,P5-bis(5'-adenozil)pentafosfat + H2O ATP + ADP
- (3) P1,P4-bis(5'-adenozil)tetrafosfat + H2O ATP + AMP
Za dejstvo ovog enzim je neophodno prisustvo dvovalentnih katjona (Mn2+, Mg2+, Zn2+, i Co2+).
Reference[uredi | uredi kod]
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.