D-2-hidroksi-kiselina dehidrogenaza
Izgled
D-2-hidroksi-kiselina dehidrogenaza | |||||||||
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Identifikatori | |||||||||
EC broj | 1.1.99.6 | ||||||||
CAS broj | 9028-83-5 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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D-2-hidroksi-kiselina dehidrogenaza (EC 1.1.99.6, D-2-hidroksi kiselinska dehidrogenaza, (R)-2-hidroksi-kiselina:(akceptor) 2-oksidoreduktaza) je enzim sa sistematskim imenom (R)-2-hidroksi-kiselina:akceptor 2-oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (R)-laktat + akceptor piruvat + redukovani akceptor
Ovaj enzim je cinkov flavoprotein (FAD). On deluje na više (R)-2-hidroksi kiselina.
- ↑ Gregolin, C., Singer, T.P., Kearney, E.B. and Boeri, E. (1961). „The formation and enzymatic properties of the various lactic dehydrogenases of yeast”. Ann. N.Y. Acad. Sci. 94: 780-797. PMID 13901630.
- ↑ Nygaard, A.P. (1961). „D-(-)-Lactate cytochrome c reductase, a flavoprotein from yeast”. J. Biol. Chem. 236: 920-925. PMID 13729965.
- ↑ Tubbs, P.K. and Greville, G.D. (1959). „Dehydrogenation of D-lactate by a soluble enzyme from kidney mitochondria”. Biochim. Biophys. Acta 34: 290-291. PMID 13839714.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
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