Barbituraza

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Barbituraza
Identifikatori
EC broj 3.5.2.1
CAS broj 9025-16-5
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Barbituraza (EC 3.5.2.1) je enzim sa sistematskim imenom barbiturat amidohidrolaza (formira 3-okso-3-ureidopropanoat).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

barbiturat + H2O 3-okso-3-ureidopropanoat

Ovaj enziom sadrži cink.

Reference[uredi - уреди | uredi izvor]

  1. Hayaishi, O. and Kornberg, A. (1952). "Metabolism of cytosine, thymine, uracil, and barbituric acid by bacterial enzymes". J. Biol. Chem. 197: 717–723. PMID 12981104. 
  2. Soong, C.L., Ogawa, J. and Shimizu, S. (2001). "Novel amidohydrolytic reactions in oxidative pyrimidine metabolism: analysis of the barbiturase reaction and discovery of a novel enzyme, ureidomalonase". Biochem. Biophys. Res. Commun. 286: 222–226. PMID 11485332. 
  3. Soong, C.L., Ogawa, J., Sakuradani, E. and Shimizu, S. (2002). "Barbiturase, a novel zinc-containing amidohydrolase involved in oxidative pyrimidine metabolism". J. Biol. Chem. 277: 7051–7058. PMID 11748240. 

Literatura[uredi - уреди | uredi izvor]

Vanjske veze[uredi - уреди | uredi izvor]