Aspartatna racemaza
(Preusmjereno sa stranice Aspartat racemaza)
| Aspartatna racemaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.1.1.13 | ||||||||
| CAS broj | 37237-56-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Aspartatna racemaza (EC 5.1.1.13, D-aspartatna racemaza, McyF) je enzim sa sistematskim imenom aspartat racemaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-aspartat D-aspartat
Ovaj enzim takođe deluje, upola manjom brzinom, na L-alanin.
Reference[uredi | uredi kod]
- ↑ Lamont, H.C., Staudenbauer, W.L. and Strominger, J.L. (1972). „Partial purification and characterization of an aspartate racemase from Streptococcus faecalis”. J. Biol. Chem. 247: 5103-5106. PMID 4626916.
- ↑ Yamauchi, T., Choi, S.Y., Okada, H., Yohda, M., Kumagai, H., Esaki, N. and Soda, K. (1992). „Properties of aspartate racemase, a pyridoxal 5′-phosphate-independent amino acid racemase”. J. Biol. Chem. 267: 18361-18364. PMID 1526977.
- ↑ Liu, L., Iwata, K., Kita, A., Kawarabayasi, Y., Yohda, M. and Miki, K. (2002). „Crystal structure of aspartate racemase from Pyrococcus horikoshii OT3 and its implications for molecular mechanism of PLP-independent racemization”. J. Mol. Biol. 319: 479-489. PMID 12051922.
- ↑ Sielaff, H., Dittmann, E., Tandeau De Marsac, N., Bouchier, C., von Döhren, H., Börner, T. and Schwecke, T. (2003). „The mcyF gene of the microcystin biosynthetic gene cluster from Microcystis aeruginosa encodes an aspartate racemase”. Biochem. J. 373: 909-916. PMID 12713441.
- ↑ Yamashita, T., Ashiuchi, M., Ohnishi, K., Kato, S., Nagata, S. and Misono, H. (2004). „Molecular identification of monomeric aspartate racemase from Bifidobacterium bifidum”. Eur. J. Biochem. 271: 4798-4803. PMID 15606767.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.