Arilestaraza

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Arilestaraza
Identifikatori
EC broj 3.1.1.2
CAS broj 9032-73-9
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Arilestaraza (EC 3.1.1.2, A-esteraza, paraoksonaza, aromatična esteraza) je enzim sa sistematskim imenom aril-estar hidrolaza.[1][2][3][4][5][6][7][8] Ovaj enzim katalizuje sledeću hemijsku reakciju

fenil acetat + H2O fenol + acetat

Ovaj enzim deluje na mnoge fenolne estre.

Reference[uredi - уреди | uredi izvor]

  1. Aldridge, W.N. (1953). "Serum esterases. I. Two types of esterase (A and B) hydrolysing p-nitrophenyl acetate, propionate and butyrate and a method for their determination". Biochem. J. 53: 110–117. PMID 13032041. 
  2. Augustinsson, K.-B. and Olsson, B. (1959). "Esterases in the milk and blood plasma of swine. 1. Substrate specificity and electrophoresis studies". Biochem. J. 71: 477–484. PMID 13638253. 
  3. Bosmann, H.B. (1972). "Membrane marker enzymes. Characterization of an arylesterase of guinea pig cerebral cortex utilizing p-nitrophenyl acetate as substrate". Biochim. Biophys. Acta 276: 180–191. PMID 5047702. 
  4. Kim, D.-H., Yang, Y.-S. and Jakoby, W.B. (1990). "Nonserine esterases from rat liver cytosol". Protein Expr. Purif. 1: 19–27. PMID 2152179. 
  5. Mackness, M.I., Thompson, H.M., Hardy, A.R. and Walker, C.H. (1987). "Distinction between 'A′-esterases and arylesterases. Implications for esterase classification". Biochem. J. 245: 293–296. PMID 2822017. 
  6. Reiner, E., Aldridge, W.N. and Hoskin, C.G., ur. (1989). Enzymes Hydrolysing Organophosphorus Compounds. Chichester, UK: Ellis Horwood. str. -. 
  7. Khersonsky, O. and Tawfik, D.S. (2005). "Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase". Biochemistry 44: 6371–6382. PMID 15835926. 
  8. Draganov, D.I., Teiber, J.F., Speelman, A., Osawa, Y., Sunahara, R. and La Du, B.N. (2005). "Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities". J. Lipid Res. 46: 1239–1247. PMID 15772423. 

Literatura[uredi - уреди | uredi izvor]

  • Reiner, E., Aldridge, W.N. and Hoskin, C.G., ur. (1989). Enzymes Hydrolysing Organophosphorus Compounds. Chichester, UK: Ellis Horwood. str. -. 

Vanjske veze[uredi - уреди | uredi izvor]