Antranilatna sintaza

Iz Wikipedije, slobodne enciklopedije
Idi na navigaciju Idi na pretragu
Antranilatna sintaza
1i7q.jpg
Antranilatna sintaza heterotetramer, Serratia marcescens
Identifikatori
EC broj 4.1.3.27
CAS broj 9031-59-8
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum

Antranilatna sintaza (EC 4.1.3.27, antranilatna sintetaza, horizmatna piruvat-lijaza (amino prihvatajuća), TrpE) je enzim sa sistematskim imenom horizmat piruvat-lijaza (amino prihvatajuća; formira antranilat).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju

horizmat + L-glutamin antranilat + piruvat + L-glutamat

U pojedinim organizmima ovaj enzim je deo multifunkcionalnog proteina.

Reference[uredi - уреди | uredi izvor]

  1. Baker, T. and Crawford, I.P. (1966). „Anthranilate synthetase. Partial purification and some kinetic studies on the enzyme from Escherichia coli”. J. Biol. Chem. 241: 5577-5584. PMID 5333199. 
  2. Creighton, T.E. and Yanofsky, C. (1970). „Chorismate to tryptophan (Escherichia coli) - anthranilate synthetase, PR transferase, PRA isomerase, InGP synthetase, tryptophan synthetase”. Methods Enzymol. 17A: 365-380. 
  3. Hütter, R., Niederberger, P. and DeMoss, J.A. (1986). „Tryptophan synthetic genes in eukaryotic microorganisms”. Annu. Rev. Microbiol. 40: 55-77. PMID 3535653. 
  4. Ito, J. and Yanofsky, C. (1969). „Anthranilate synthetase, an enzyme specified by the tryptophan operon of Escherichia coli: Comparative studies on the complex and the subunits”. J. Bacteriol. 97: 734-742. PMID 4886290. 
  5. Zalkin, H. and Kling, D. (1968). „Anthranilate synthetase. Purification and properties of component I from Salmonella typhimurium”. Biochemistry 7: 3566-3573. PMID 4878701. 

Literatura[uredi - уреди | uredi izvor]

Vanjske veze[uredi - уреди | uredi izvor]