Antranilatna sintaza
| Antranilatna sintaza | |||||||||
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| Antranilatna sintaza heterotetramer, Serratia marcescens | |||||||||
| Identifikatori | |||||||||
| EC broj | 4.1.3.27 | ||||||||
| CAS broj | 9031-59-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | structures | ||||||||
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Antranilatna sintaza (EC 4.1.3.27, antranilatna sintetaza, horizmatna piruvat-lijaza (amino prihvatajuća), TrpE) je enzim sa sistematskim imenom horizmat piruvat-lijaza (amino prihvatajuća; formira antranilat).[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
U pojedinim organizmima ovaj enzim je deo multifunkcionalnog proteina.
Reference[uredi - уреди | uredi izvor]
- ↑ Baker, T. and Crawford, I.P. (1966). "Anthranilate synthetase. Partial purification and some kinetic studies on the enzyme from Escherichia coli". J. Biol. Chem. 241: 5577–5584. PMID 5333199.
- ↑ Creighton, T.E. and Yanofsky, C. (1970). "Chorismate to tryptophan (Escherichia coli) - anthranilate synthetase, PR transferase, PRA isomerase, InGP synthetase, tryptophan synthetase". Methods Enzymol. 17A: 365–380.
- ↑ Hütter, R., Niederberger, P. and DeMoss, J.A. (1986). "Tryptophan synthetic genes in eukaryotic microorganisms". Annu. Rev. Microbiol. 40: 55–77. PMID 3535653.
- ↑ Ito, J. and Yanofsky, C. (1969). "Anthranilate synthetase, an enzyme specified by the tryptophan operon of Escherichia coli: Comparative studies on the complex and the subunits". J. Bacteriol. 97: 734–742. PMID 4886290.
- ↑ Zalkin, H. and Kling, D. (1968). "Anthranilate synthetase. Purification and properties of component I from Salmonella typhimurium". Biochemistry 7: 3566–3573. PMID 4878701.
Literatura[uredi - уреди | uredi izvor]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. http://books.google.com/books/about/Fundamentals_of_enzymology.html?id=8uvwAAAAMAAJ.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. http://books.google.com/books/about/Advances_in_Enzymology_and_Related_Areas.html?id=Pmh8yToeuloC.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. http://www.garlandscience.com/textbooks/0815323042.asp?type=reviews.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. http://books.google.com/books/about/Enzyme_Kinetics.html?id=T60oAAAAYAAJ.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. http://books.google.com/books/about/Evaluation_of_Enzyme_Inhibitors_in_Drug.html?id=l2rMy8QNUk0C.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. http://books.google.com/books/about/Biochemical_pathways.html?id=081qAAAAMAAJ.
Vanjske veze[uredi - уреди | uredi izvor]
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