Aminodezoksihorizmatna lijaza
| Aminodezoksihorizmatna lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.3.38 | ||||||||
| CAS broj | 132264-33-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Aminodezoksihorizmatna lijaza (EC 4.1.3.38, enzim X, 4-amino-4-dezoksihorizmat lijaza, 4-amino-4-dezoksihorizmat piruvat-lijaza) je enzim sa sistematskim imenom 4-amino-4-dezoksihorizmat piruvat-lijaza (formira 4-aminobenzoat).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 4-amino-4-dezoksihorizmat 4-aminobenzoat + piruvat
Ovaj enzim je piridoksal-fosfatni protein.
- ↑ Ye, Q.Z., Liu, J. and Walsh, C.T. (1990). „p-Aminobenzoate synthesis in Escherichia coli: purification and characterization of PabB as aminodeoxychorismate synthase and enzyme X as aminodeoxychorismate lyase”. Proc. Natl. Acad. Sci. USA 87: 9391-9395. PMID 2251281.
- ↑ Green, J.M., Merkel, W.K. and Nichols, B.P. (1992). „Characterization and sequence of Escherichia coli pabC, the gene encoding aminodeoxychorismate lyase, a pyridoxal phosphate-containing enzyme”. J. Bacteriol. 174: 5317-5323. PMID 1644759.
- ↑ Nakai, T., Mizutani, H., Miyahara, I., Hirotsu, K., Takeda, S., Jhee, K.H., Yoshimura, T. and Esaki, N. (2000). „Three-dimensional structure of 4-amino-4-deoxychorismate lyase from Escherichia coli”. J. Biochem. 128: 29-38. PMID 10876155.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.