Alkilgliceron-fosfat sintaza
| Alkilgliceron-fosfat sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.5.1.26 | ||||||||
| CAS broj | 102484-74-2&title= 64060-42-0, 102484-74-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Alkilgliceron-fosfat sintaza (EC 2.5.1.26, alkildihidroksiacetonfosfatna sintaza, alkildihidroksiaceton fosfatna sintetaza, alkil DHAP sintetaza, alkil-DHAP, dihidroksiaceton-fosfatna aciltransferaza, DHAP-AT) je enzim sa sistematskim imenom 1-acil-gliceron-3-fosfat:dugolančani-alkohol O-3-fosfo-2-oksopropaniltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 1-acil-gliceron 3-fosfat + dugolančani alkohol alkil-gliceron 3-fosfat + dugolančani kiselinski anion
Estarski vezana masna kiselina supstrata se odvaja i zamenjuje dugolančanim alkoholom etarski vezanim.
- ↑ Brown, A.J. and Snyder, F. (1982). „Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism”. J. Biol. Chem. 257: 8835-8839. PMID 7096336.
- ↑ Wykle, R.L., Piantadosi, C. and Snyder, F. (1972). „The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor”. J. Biol. Chem. 247: 2944-2948. PMID 4401994.
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