Aldozna 1-epimeraza
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| Aldozna 1-epimeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.1.3.3 | ||||||||
| CAS broj | 9031-76-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Aldozna 1-epimeraza (EC 5.1.3.3, mutarotaza, aldozna mutarotaza, galaktozna mutarotaza, galaktozna 1-epimeraza, D-galaktozna 1-epimeraza) je enzim sa sistematskim imenom aldoza 1-epimeraza.[1][2][3][4][5][6][7] Ovaj enzim katalizuje sledeću hemijsku reakciju
- alfa-D-glukoza beta-D-glukoza
Ovaj enzim takođe deluje na L-arabinozu, D-ksiloza, D-galaktozu, maltozu i laktozu.
Reference[uredi | uredi kod]
- ↑ Bentley, R. and Bhate, D.S. (1960). „Mutarotase from Penicillium notatum. I. Purification, assay, and general properties of the enzyme”. J. Biol. Chem. 235: 1219-1224. PMID 13799037.
- ↑ Bentley, R. and Bhate, D.S. (1960). „Mutarotase from Penicillium notatum. II. The mechanism of the mutarotation reaction”. J. Biol. Chem. 235: 1225-1233. PMID 13799038.
- ↑ Keilin, D. and Hartree, E.F. (1952). „Biological catalysis of mutarotation of glucose”. Biochem. J. 50: 341-348. PMID 14915955.
- ↑ Levy, G.B. and Cook, E.S. (1954). „A rotographic study of mutarotase”. Biochem. J. 57: 50-55. PMID 13159947.
- ↑ Beebe, J.A. and Frey, P.A. (1998). „Galactose mutarotase: purification, characterization, and investigations of two important histidine residues”. Biochemistry 37: 14989-14997. PMID 9778377.
- ↑ Thoden, J.B., Timson, D.J., Reece, R.J. and Holden, H.M. (2004). „Molecular structure of human galactose mutarotase”. J. Biol. Chem. 279: 23431-23437. PMID 15026423.
- ↑ Thoden, J.B., Kim, J., Raushel, F.M. and Holden, H.M. (2003). „The catalytic mechanism of galactose mutarotase”. Protein Sci. 12: 1051-1059. PMID 12717027.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.