Acetilgalaktozaminil-O-glikozil-glikoprotein b-1,3-N-acetilglukozaminiltransferaza
Izgled
Acetilgalaktozaminil-O-glikozil-glikoprotein b-1,3-N-acetilglukozaminiltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.4.1.147 | ||||||||
CAS broj | 87927-96-6 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Acetilgalaktozaminil-O-glikozil-glikoprotein b-1,3-N-acetilglukozaminiltransferaza (EC 2.4.1.147, O-glikozil-oligosaharid-glikoprotein N-acetilglukozaminiltransferaza III, uridin difosfoacetilglukozamin-mucin beta(1->3)-acetilglukozaminiltransferaza, mucinska osnova 3 beta3-GlcNAc-transferaza, UDP-N-acetil-D-glukozamin:O-glikozil-glikoprotein (N-acetil-D-glukozamin na N-acetil-D-galaktozaminil-R) beta-1,3-N-acetil-D-glukozaminiltransferaza) je enzim sa sistematskim imenom UDP-N-acetil-D-glukozamin:N-acetil-beta-D-galaktozaminil-R 3-beta-N-acetil-D-glukozaminiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- UDP-N-acetil-D-glukozamin + N-acetil-beta-D-galaktozaminil-R UDP + N-acetil-beta-D-glukozaminil-(1->3)-N-acetil-beta-D-galaktozaminil-R
- EC 2.4.1.102 (beta-1,3-galaktozil-O-glikozil-glikoprotein beta-1,6-N-acetilglukozaminiltransferaza)
- EC 2.4.1.146 (beta-1,3-galaktozil-O-glikozil-glikoprotein beta-1,3-N-acetilglukozaminiltransferaza)
- EC 2.4.1.148 (acetilgalaktozaminil-O-glikozil-glikoprotein beta-1,6-N-acetilglukozaminiltransferaza)
- ↑ Brockhausen, I., Rachaman, E.S., Matta, K.L. and Schachter, H. (1983). „The separation by liquid chromatography (under elevated pressure) of phenyl, benzyl, and O-nitrophenyl glycosides of oligosaccharides. Analysis of substrates and products for four N-acetyl-D-glucosaminyl-transferases involved in mucin synthesis”. Carbohydr. Res. 120: 3-16. PMID 6226356.
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