4-Hidroksiglutamat transaminaza
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| 4-Hidroksiglutamat transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.23 | ||||||||
| CAS broj | 37277-86-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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4-Hidroksiglutamat transaminaza (EC 2.6.1.23, 4-hidroksiglutamatna aminotransferaza) je enzim sa sistematskim imenom 4-hidroksi-L-glutamat:2-oksoglutarat aminotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 4-hidroksi-L-glutamat + 2-oksoglutarat 4-hidroksi-2-oksoglutarat + L-glutamat
Oksaloacetat može da zameni 2-oksoglutarat.
Reference[uredi | uredi kod]
- ↑ Goldstone, A. and Adams, E. (1962). „Metabolism of γ-hydroxyglutamic acid. I. Conversion to α-hydroxy-γ-ketoglutarate by purified glutamic-aspartic transaminase to rat liver”. J. Biol. Chem. 237: 3476-3485. PMID 13948827.
- ↑ Kuratomi, K., Fukunaga, K. and Kobayashi, Y. (1963). „The metabolism of γ-hydroxyglutamate in rat liver. II. A transaminase concerned in γ-hydroxyglutamate metabolism”. Biochim. Biophys. Acta 78: 629-636. PMID 14089443.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.