2-oksopropil-KoM reduktaza (karboksilacija)
| 2-oksopropil-KoM reduktaza (karboksilacija) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.8.1.5 | ||||||||
| CAS broj | 244301-63-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
2-oksopropil-KoM reduktaza (karboksilacija) (EC 1.8.1.5, NADPH:2-(2-ketopropiltio)etansulfonat oksidoreduktaza/karboksilaza, NADPH:2-ketopropil-koenzim M oksidoreduktaza/karboksilaza) je enzim sa sistematskim imenom 2-merkaptoetansulfonat,acetoacetat:NADP+ oksidoreduktaza (dekarboksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2-merkaptoetansulfonat + acetoacetat + NADP+ 2-(2-oksopropiltio)etansulfonat + CO2 + NADPH
Ovaj enzim takođe deluje na tioetre.
- ↑ Allen, J.R., Clark, D.D., Krum, J.G. and Ensign, S.A. (1999). „A role for coenzyme M (2-mercaptoethanesulfonic acid) in a bacterial pathway of aliphatic epoxide carboxylation”. Proc. Natl. Acad. Sci. USA 96: 8432-8437. PMID 10411892.
- ↑ Clark, D.D., Allen, J.R. and Ensign, S.A. (2000). „Characterization of five catalytic activities associated with the NADPH:2-ketopropyl-coenzyme M [2-(2-ketopropylthio)ethanesulfonate] oxidoreductase/carboxylase of the Xanthobacter strain Py2 epoxide carboxylase system”. Biochemistry 39: 1294-1304. PMID 10684609.
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